No Priors: Artificial Intelligence | Technology | Startups

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At this moment of inflection in technology, co-hosts Elad Gil and Sarah Guo talk to the world's leading AI engineers, researchers and founders about the biggest questions: How far away is AGI? What markets are at risk for disruption? How will commerce, culture, and society change? What’s happening in state-of-the-art in research? “No Priors” is your guide to the AI revolution. Email feedback to show@no-priors.com.Sarah Guo is a startup investor and the founder of Conviction, an investment firm purpose-built to serve intelligent software, or "Software 3.0" companies. She spent nearly a decade incubating and investing at venture firm Greylock Partners.Elad Gil is a serial entrepreneur and a startup investor. He was co-founder of Color Health, Mixer Labs (which was acquired by Twitter). He has invested in over 40 companies now worth $1B or more each, and is also author of the High Growth Handbook.

Recent Episodes
  • Predicting the Earth with Josh Goldman: How KoBold Uses AI to Find Critical Minerals
    Apr 17, 2025 – 40:53
  • From Job Displacement to AI Trainers, Brendan Foody on Work in the AI Age
    Apr 10, 2025 – 41:52
  • Public Markets, Image Gen, and Specialized Models, with Sarah and Elad
    Apr 3, 2025 – 27:44
  • Conversations Are the Source of Truth in Healthcare with Abridge CEO Shiv Rao
    Mar 27, 2025 – 38:42
  • The Robotics Revolution, with Physical Intelligence’s Cofounder Chelsea Finn
    Mar 20, 2025 – 35:14
  • Copilot, Agent Mode, and the New World of Dev Tools with GitHub’s CEO Thomas Dohmke
    Mar 13, 2025 – 50:34
  • National Security Strategy and AI Evals on the Eve of Superintelligence with Dan Hendrycks
    Mar 5, 2025 – 36:24
  • Building the Platform for Scientific Breakthrough, with Noubar Afeyan of Moderna and Flagship Pioneering
    Feb 27, 2025 – 40:32
  • Virtual Cell Models, Tahoe-100 and Data for AI-in-Bio with Vevo Therapeutics and the Arc Institute
    Feb 25, 2025 – 57:40
  • Building Hard Tech in Hard Markets: Kyle Vogt on Cruise, Twitch, and The Bot Company
    Feb 20, 2025 – 38:14
  • How Harvey AI is Changing the Legal Industry with Winston Weinberg
    Feb 14, 2025 – 49:35
  • DeepSeek, Deep Research, and 2025 Predictions with Sarah and Elad
    Feb 7, 2025 – 22:32
  • Rick Caruso on LA’s Wildfires, Policy Failures, and the Path Forward
    Jan 30, 2025 – 27:11
  • What Can We Do About Wildfires? With Convective Capital’s Bill Clerico
    Jan 23, 2025 – 37:59
  • How AI Agents Are Transforming Customer Support, with Decagon’s Jesse Zhang
    Jan 16, 2025 – 30:09
  • Erik Bernhardsson on Creating Tools That Make AI Feel Effortless
    Jan 9, 2025 – 23:36
  • The Best of 2024 with Sarah Guo and Elad Gil
    Dec 26, 2024 – 27:07
  • Revolutionizing Customer Success with Agency’s Elias Torres
    Dec 19, 2024 – 31:18
  • How Diamond Cooling Could Power the Future of AI, with Akash Systems
    Dec 12, 2024 – 42:21
  • Bolt’s Eric Simons on Enabling Everyone to Generate Websites with AI
    Dec 5, 2024 – 38:17
  • Model Plateaus and Enterprise AI Adoption with Cohere's Aidan Gomez
    Nov 21, 2024 – 44:15
  • AI and the Future of Math, with DeepMind’s AlphaProof Team
    Nov 14, 2024 – 39:21
  • NVIDIA's Jensen Huang on AI Chip Design, Scaling Data Centers, and his 10-Year Bets
    Nov 7, 2024 – 36:53
  • Forecasting the Future with Kalshi: America’s First Regulated Prediction Market
    Oct 31, 2024 – 35:36
  • Waymo’s Journey to Full Autonomy: AI Breakthroughs, Safety, and Scaling
    Oct 24, 2024 – 44:30
  • Gaming, Nobel Prizes and At-Risk Businesses in the AI Era
    Oct 17, 2024 – 29:29
  • Launching AI products with Braintrust’s CEO Ankur Goyal
    Oct 8, 2024 – 38:28
  • The Sheriff of Silicon Valley: Lina Khan’s FTC agenda for M&A, AI Acquisitions, and Non-Competes
    Oct 3, 2024 – 26:08
  • Using AI to evaluate employee performance with Rippling’s COO Matt MacInnis
    Sep 25, 2024 – 31:28
  • Transforming Customer Service through Company Agents, with Sierra’s Bret Taylor
    Sep 19, 2024 – 48:30
  • Future of LLM Markets, Consolidation, and Small Models with Sarah and Elad
    Sep 12, 2024 – 26:28
  • The Road to Autonomous Intelligence with Andrej Karpathy
    Sep 5, 2024 – 44:16
  • Building toward a bright post-AGI future with Eric Steinberger from Magic.dev
    Aug 30, 2024 – 37:49
  • Cloud Strategy in the AI Era with Matt Garman, CEO of AWS
    Aug 29, 2024 – 42:58
  • The marketplace for AI compute with Jared Quincy Davis from Foundry
    Aug 22, 2024 – 43:12
  • How AI can help build smarter systems for every team with Eric Glyman and Karim Atiyeh of Ramp
    Aug 15, 2024 – 48:50
  • Innovating Spend Management through AI with Pedro Franceschi from Brex
    Aug 8, 2024 – 33:39
  • Google DeepMind's Vision for AI, Search and Gemini with Oriol Vinyals from Google DeepMind
    Aug 1, 2024 – 46:08
  • Low-Code in the Age of AI and Going Enterprise, with Howie Liu from Airtable
    Jul 25, 2024 – 41:25
  • How AI is opening up new markets and impacting the startup status quo with Sarah Guo and Elad Gil
    Jul 18, 2024 – 29:12
  • The Best of 2024 (so far) with Sarah Guo and Elad Gil
    Jul 11, 2024 – 25:56
  • State Space Models and Real-time Intelligence with Karan Goel and Albert Gu from Cartesia
    Jun 27, 2024 – 34:08
  • Can AI replace the camera? with Joshua Xu from HeyGen
    Jun 20, 2024 – 27:26
  • How the ARC Prize is democratizing the race to AGI with Mike Knoop from Zapier
    Jun 11, 2024 – 26:03
  • The evolution and promise of RAG architecture with Tengyu Ma from Voyage AI
    Jun 6, 2024 – 36:20
  • How YC fosters AI Innovation with Garry Tan
    May 23, 2024 – 39:59
  • The Data Foundry for AI with Alexandr Wang from Scale
    May 22, 2024 – 39:00
  • Music consumers are becoming the creators with Suno CEO Mikey Shulman
    May 16, 2024 – 30:26
  • Context windows, computer constraints, and energy consumption with Sarah and Elad
    May 9, 2024 – 29:10
  • Cognition’s Scott Wu on how Devin, the AI software engineer, will work for you
    May 2, 2024 – 29:28
Recent Reviews
  • RowanLo
    Boring/ Sleep Noise
    This podcast is extremely boring. I fell asleep twice while typing this review. I understand the subject matter isn’t exactly exciting but you’re literally putting your listeners to sleep.
  • Nubian Lyaness
    Best podcast on ai and technology
    Sometimes very technical but great range of guests and questions. This is one for the weekly listen.
  • Caduce07
    One of the best
    Weekly listen for pioneers in AI
  • Winston2356
    Good company marketing w a bit of analysis
    The episodes play like a vendor Presentstion. Here’s what my company is about, what our product does, how we see it improving. There’s a little bit of a broader view on implications but always it’s about what my company is doing. For some, this is probably what they want. But I’ve sat thru so many vendor presentations, it’s just not for me anymore.
  • PeteSteg
    Staying on the cutting edge of AI
    Gilad and Sarah are on the pulse of AI. This is a great show if you are pushing the edge in AI with your business and need to stay up-to-date. An example: a fabulous “best cuts” show highlighting the best from 2023’s episodes. It’s great to find an efficient way to keep up!
  • dogstechcoffee
    The people to learn from
    Huge fan of the podcast and Sarah’s work. Short, succinct, and direct - love the lack of filler. Thanks!!
  • DB@BM
    Love it
    Deeply fascinating discussions at the forefront of AI innovation, with sharp insights on the direction of tech and market.
  • OGWallStreet
    My favorite AI podcast
    Love the show! Sarah and Elad bring on incredible AI leaders to discuss their work and where they see the future of AI going, all while keeping it fun and listener-friendly.
  • GoUltimate
    Just excellent.
    No Priors is a must-listen if you want to get smart on GenAI and how it’s impacting every part of the technology stack. Guests are second-to-none and Elad and Sarah manage to ask questions germane to both new-comers and industry insiders.
  • SVB Jack
    Love this podcast!
    Really enjoy hearing Sarah and Elad’s perspectives on AI trends and use cases. They cover such a great breadth of stories and use cases with amazing founders. Thanks for sharing!
  • psshank
    Insightful. Intriguing. Diverse topics.
    A must listen for AI/Ml enthusiasts, founders & builders. I love the diversity of AI topics on this podcast and the detailed chats. Sarah & Elad do a great job of asking the right questions and letting the guests speak & share their insights. And the guests are not just a Who’s Who of AI but hidden gems in the industry.
  • Zach Merritt - Data
    Incredible way to learn
    Amazing new podcast on all things AI. I’ve always used podcasts as my number one way to learn. I went to grad school for data science and swear I’ve learned the majority of what I know from podcasts. With the new LLM revolution, I felt there wasn’t any podcasts really hitting the mark - until No Priors. Sarah and Elad are a joy, so smart, and bring on incredible guests.
  • krish.chainani
    GREAT SHOW
    I’ve been a big fan of Elad for a while now. I watched a few episodes of the podcast and now I can say that I think I like Sarah even more! They both have a methodical but not over steering way of leading conversations while giving their guests complete control of completing their chain of thought. I’m subscribed weekly!
  • Zrm11
    Great show!
    one of the best new shows I have tried in the past year!
  • GTPE88
    THE AI Show
    Sarah and Elad bring in industry experts to talk about AI in every show. A great listen to keep up with the latest trends and tooling in AI.
  • Nathan lands
    One of my favorite podcasts
    I’m a huge fan of No Priors and Sarah and Elad. As the creator of the Lore.com AI newsletter, I find the discussions highly insightful. Some of the interviews have helped me to think more deeply about where things are going with AI and VC and influenced some of my content. If you’re interested in AI and how it might impact your business or work, I highly suggest you subscribe and listen.
  • FabianVidela
    Great Podcast to stay up to date on A.I.
    I found this show to be a great way to keep up to date with trends and tooling around A.I. Great guests, good format, Recommended!
  • haryson465
    Love this show!
    I’ve been loving your podcast! Best podcast ever!! For sure need more episodes!! Keep up the good work!
  • rsarver
    Favorite AI podcast
    Sarah and Elad both really know their stuff and have had great guests on. Love it so far
  • Marky_Kim
    The Antithesis of Shallow and Pedantic
    10 years into listening to podcasts, this is my first ever review. Sarah and Elad are behemoths in the industry. The fact that they are sharing these interviews and insights is an absolute blessing for everyone. I wanna keep this podcast to myself (cuz it’s such a gem!) but I know that my friends will benefit immensely from No Priors. Keep up the good work! For those that don’t know, Elad also posts a ton of content on his blog and YouTube channel. Sarah’s blog is incredible as well — one of the coolest websites I have seen!
  • guessmonster
    Great Balance between Intrigue and Depth
    Glad and Sarah manage to keep topics approachable and relatable while still revealing nuanced debates within the AI community.
  • AnonEtcher
    A must listen!
    Insightful guests and varied discussion, I always come away from this podcast with new learnings. Amidst all the AI hype - this is one show that cuts through the clutter. Highly recommend.
  • anonymous6537865262546
    Very well thought out discussions
    Definitely a great podcast to follow to stay ahead of the curve when it comes to AI. Sarah and Elad are some of the smartest investors in the industry.
  • neeerdette
    Weekly in-depth AI discussion
    Excellent guests, a way to stay updated on the landscape and hang out with friends. Also, Elad and Sarah have smooth as butter voices. - Sarah Guo
  • LG. 12
    Brilliant
    The best AI podcast!
  • Scott_Kelly
    Insightful AI Podcast
    It really does not get more cutting edge than this in the world of AI. It takes a host(s) who know the business today and where it may go (or not) to not only inform the audience, the risks involved, and also to simplify the subject at hand for even the most novice minds into the investment world.
  • Chris Conforti
    Awesome content & speakers
    Sarah & Elad are thought leaders and assemble an awesome group of experts - worth a listen every time
  • as612
    Best AI and tech podcast out there!
    With an A+ guest list of the next generation of AI companies transforming industries
  • iheartsg
    Excellent
    If you are into learning about game changing tech and how it will change our world this is a must listen. Love these hosts and awesome guests so far. I am looking forward to what they put out next!
  • somewhere in the bay
    Must listen
    Wow it’s incredible where AI is going! Listen to super smart people talk about mind blowing topics. The tech podcast scene has needed something new for a while now and this is a breath of fresh air!
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